Discover the most trusted telehealth providers offering GLP-1 prescriptions for weight loss.

1
ro image
ro rating

Ro.co

  • Get started for just $39, then as low as $74/month with annual plan paid upfront
  • FDA-approved GLP-1s at the lowest prices available, whether you're covered or not
  • Access to the Wegovy® (semaglutide) GLP-1 pill, if prescribed
ro rating
Go to Ro.co
arrow imageLeaving WebMD
Go to Ro.co
arrow imageLeaving WebMD
2
welludr. image
welludr. rating image

welludr.

  • Compounded semaglutide from $49/mo — cancel or change anytime
  • Unlimited clinician messaging + same-day appointment slots
  • New customer offer: lock in $150 off every month — for life
welludr. rating image
Go to welludr.
arrow imageLeaving WebMD
Go to welludr.
arrow imageLeaving WebMD
3
embody rating image

Embody

  • Exclusive: Semaglutide for $69/month or Tirzepatide for $119/month
  • Keep your price for life - regardless of dose or month
  • Includes online visit, free shipping, delivered to your door
embody rating image
Go to Embody
arrow imageLeaving WebMD
Go to Embody
arrow imageLeaving WebMD
4
trimi image
trimi rating image

Direct Meds

  • Exclusive Offer: Semaglutide $69 or Tirzepatide just $119, locked for life
  • US-certified pharmacy, direct-to-pharmacy pricing, no middleman markup
  • 4.6 on Trustpilot, BBB accredited, trusted by 300,000+ patients
trimi rating image
Go to Direct Meds
arrow imageLeaving WebMD
Go to Direct Meds
arrow imageLeaving WebMD
5
medvi image
medvi rating image

MEDVi

  • Semaglutide $149/mo Forever or Tirzepatide $238/mo Forever
  • FREE 1-on-1 Provider Visits, Dietitian Support & Care Coaching
  • Summer Offer: Save $140 Today — Medication Always Included
medvi rating image
Go to MEDVi
arrow imageLeaving WebMD
Go to MEDVi
arrow imageLeaving WebMD
6
snagrx image
snagrx rating image

SnagRx

  • Exclusive Rate: $69/month Semaglutide, $119/month Tirzepatide
  • One price, forever - no increases as your dose changes
  • Covers your online visit and free cold shipped to your door
snagrx rating image
Go to SnagRx
arrow imageLeaving WebMD
Go to SnagRx
arrow imageLeaving WebMD
7
sprout image
sprout rating image

Sprout Health

  • Real humans, not bots; support whenever you need it
  • $150 OFF per month & more on longer-term plans. Forever, regardless of dose
  • US-licensed Clinicians, LegitScript Certified, Cancel Anytime
sprout rating image
Go to Sprout Health
arrow imageLeaving WebMD
Go to Sprout Health
arrow imageLeaving WebMD
8
bb-health rating image

Bodybuilding Health+

  • Injectable Semaglutide starting from $141.50/month, if prescribed
  • Clinically proven weight support from the #1 fitness brand
  • Save $100 on your first month, no membership or hidden fees
bb-health rating image
Go to Bodybuilding Health+
arrow imageLeaving WebMD
Go to Bodybuilding Health+
arrow imageLeaving WebMD

Achieve Your Weight Loss Goals

If you've struggled with weight loss, persistent hunger, or limited results from diet and exercise alone, GLP-1 weight loss medications like semaglutide may offer a clinically supported solution. Prescribed by licensed providers and backed by medical research, GLP-1 treatments help regulate appetite and support sustainable weight loss through personalized, supervised care.

For individuals seeking a structured approach to weight loss, a trusted GLP-1 telehealth provider can offer clinically supported care and ongoing oversight.

Top Choice

1
ro image
ro rating

Ro.co

  • Get started for just $39, then as low as $74/month with annual plan paid upfront
  • FDA-approved GLP-1s at the lowest prices available, whether you're covered or not
  • Access to the Wegovy® (semaglutide) GLP-1 pill, if prescribed
  • Free GLP-1 insurance check
ro rating
Go to Ro.co
arrow imageLeaving WebMD
Go to Ro.co
arrow imageLeaving WebMD

How Effective Are GLP-1 Medications for Weight Loss?

GLP-1 receptor agonists including Wegovy® and Ozempic® (semaglutide) — are prescription medications originally developed to treat type 2 diabetes.1 In recent years, semaglutide has also been widely studied for medical weight management, with Wegovy® (semaglutide) specifically approved for chronic weight loss in eligible adults.

Clinical trials have shown that semaglutide can help some adults lose meaningful amounts of weight when combined with lifestyle changes. In large studies of Wegovy® (semaglutide), participants lost 14–15% of their body weight on average over approximately 68 weeks.2 Individual results vary, and treatment requires evaluation and ongoing supervision by a licensed healthcare provider.

Interest in GLP-1 medications has grown significantly as more people look for medically guided options beyond traditional diet and exercise alone. Many telehealth providers now offer online consultations to determine whether treatments like Wegovy® (semaglutide) or Zepbound® (tirzepatide) may be appropriate.

Comparing FDA-Approved GLP-1 Treatments

Both semaglutide and tirzepatide are effective GLP-1 treatments, but are sold under different brand names approved for different primary uses.

Wegovy® (semaglutide)

  • FDA-approved specifically for chronic weight management
  • Higher maintenance dose designed for weight loss, extensively studied in obesity clinical trials
  • Available in both injection form and as the only FDA-approved semaglutide pill for weight loss in adults3
  • Typically prescribed for adults with obesity, or excess weight with at least one weight-related condition

Tirzepatide (Zepbound®)

  • FDA-approved specifically for chronic weight management
  • Targets two hormones, GLP-1 and GIP, and has been extensively studied in obesity clinical trials4
  • Taken as a once-weekly injection, available in single-dose vials, single-dose pens, and the multi-dose Zepbound® KwikPen®
  • Typically prescribed for adults with obesity, or excess weight with at least one weight-related condition4

Ozempic® (semaglutide)

  • Approved for type 2 diabetes management
  • Sometimes prescribed off-label for weight loss
  • Lower dosing range available5

Mounjaro® (tirzepatide)

  • Approved for type 2 diabetes management4
  • Sometimes prescribed off-label for weight loss
  • Taken as a once-weekly injection

A licensed healthcare provider can help determine which option may be appropriate for you based on eligibility, medical history, weight loss goals, and coverage.

Who Can Take GLP-1s?

Typically, GLP-1s like semaglutide and tirzepatide are approved for adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol.4 GLP-1s are not recommended for people with a personal or family history of medullary thyroid carcinoma or MEN 2, or for those who are pregnant or planning a pregnancy. A licensed provider will review your health history to confirm whether a GLP-1 weight loss medication is a safe fit.

Best Value

2
welludr. image
welludr. rating image

welludr.

  • Compounded semaglutide from $49/mo — cancel or change anytime
  • Unlimited clinician messaging + same-day appointment slots
  • New customer offer: lock in $150 off every month — for life
welludr. rating image
Go to welludr.
arrow imageLeaving WebMD
Go to welludr.
arrow imageLeaving WebMD

What to Expect When You Start Semaglutide

Semaglutide is started at a low dose and increased gradually, giving your body time to adjust and helping minimize side effects. Every treatment plan is personalized, but here’s a general timeline:

Weekly Injections

Semaglutide injections are taken once a week and can be done at home. They're typically given in the abdomen, thigh, or upper arm. Until it's used, the medication is usually kept in the refrigerator, so be sure to follow the storage instructions that come with your prescription.

Weeks 1–4: Starting low

Most new qualified patients are prescribed 0.25 mg once a week to start. This starter dose helps your body adjust rather than drive major weight loss, though many people notice their appetite quieting and feel full sooner.

Weeks 5–16: Stepping up

Your dose typically increases every four weeks, from 0.5 mg to 1 mg to 1.7 mg.6 Mild side effects may return briefly after each increase, and your provider can slow the pace if needed.

Week 17 and beyond: Maintenance

Most people continue on a weekly maintenance dose of 1.7 mg or 2.4 mg.6 Semaglutide weight loss builds gradually over months, so staying consistent through the step-up phase matters.

Prefer a pill?

The Wegovy® (semaglutide) pill is taken once daily, starting at 1.5 mg and increasing monthly to a 25 mg maintenance dose.6

Potential GLP-1 Medication Side Effects

The most common side effects of GLP-1 medications are nausea, diarrhea, vomiting, constipation, and stomach pain, which are usually mild and most noticeable after a dose increase.6 Eating smaller meals, limiting greasy foods, staying hydrated, and prioritizing protein can help you stay comfortable and preserve muscle.7

How to Choose the Best GLP-1 Option for You

Choosing a GLP-1 medication involves considering your health goals, medical history, and access to ongoing care. Because all GLP-1 medications, like Wegovy® (semaglutide) and Zepbound® (tirzepatide), require a prescription, the process typically begins with a medical evaluation.

Here are a few factors to consider when comparing options:

Your health goals

Some people focus on weight loss, while others may also be managing type 2 diabetes. Eligibility and medication choice may vary.

Medical consultation and supervision

A licensed provider will review your history, current medications, and determine whether GLP-1 therapy is appropriate. Follow-up care may help adjust dosing and monitor progress.

Cost and insurance coverage

Pricing varies between providers. Some programs offer insurance support, while others provide self-pay options.

Program support

Some telehealth services include ongoing check-ins, coaching, or prescription management, which may help with long-term adherence.

Choosing a medically supervised GLP-1 program can make the process safer, more personalized, and more effective. Below, take a closer look at how each provider supports patients — from prescription access to follow-up care.

Top Choice

1
ro image
ro rating

Ro.co

  • Access to the Wegovy® (semaglutide) GLP-1 pill, if prescribed
  • FDA-approved GLP-1s at the lowest prices available, whether you're covered or not
  • Get started for just $39, then as low as $74/month with annual plan paid upfront
  • Free GLP-1 insurance check
ro rating
Go to Ro.co
arrow imageLeaving WebMD
Go to Ro.co
arrow imageLeaving WebMD

About Ro.co:

Ro provides online access to GLP-1 medications like Ozempic® (semaglutide), Wegovy® (semaglutide), Zepbound® (tirzepatide), and Foundayo™ (orforglipron), if prescribed. Consult online and get personalized treatment.

Weight Loss Treatments Offered:

The most effective medications on the market, including FDA-approved GLP-1 meds and the Wegovy® pill, and Foundayo, another oral GLP-1 medication, if prescribed. See Important Safety Information and Boxed Warning at ro.co/safety-info/glp1.

Do I Need a Prescription?

Yes. A Ro doctor will prescribe if you're eligible.

Delivery:

Medications available to ship directly or picked up from a local pharmacy, with ongoing support from healthcare providers.

Costs:

The Ro Body membership starts at $39 first month, then as low as $74 ongoing with annual prepay. Pricing includes medical consultations, follow-ups, and prescription management. Insurance assistance included for branded medications. The cost of GLP-1 medication is not included in the membership cost. Medication cost will depend on your treatment and insurance coverage.

Commitment:

No long-term contract required. Continue as needed; cancel anytime.8

Go to Ro.co
arrow imageLeaving WebMD

About welludr.

welludr. is a 100% online weight-loss program that pairs compounded semaglutide with unlimited clinician messaging, AI-enhanced progress tracking, and a 90-day money-back guarantee.

Weight Loss Treatments Offered:

welludr. offers Compounded semaglutide as a once-weekly injection, with dosing adjusted as your body responds. Brand-name Ozempic® is also available, and tirzepatide options are offered for those who qualify.

Do I Need a Prescription?

Yes — you complete a short online intake (about 15 minutes, with same-day slots available), and a U.S.-licensed clinician reviews it and builds your treatment plan if you're approved.

Delivery:

Medication ships free and discreetly from licensed U.S. pharmacies every 4 weeks, with refills sent before you run out and unlimited provider messaging for dosing and side-effect support.

Costs:

Compounded semaglutide starts at $49/mo, with brand-name Ozempic from $1,399/mo. Compounded tirzepatide starts at $89/mo, with the same price at every dosage level. A new-customer offer locks in $150 off every month for life.

Commitment:

No long-term contract is required — plans bill monthly, ship every 4 weeks, and you can cancel or change anytime.9

Go to welludr.
arrow imageLeaving WebMD

About Embody:

Embody is a GLP-1 telehealth platform trusted by 100,000+ patients, offering compounded weight loss medications with no hidden fees and no office visits.

Weight Loss Treatments Offered:

  • Compounded Semaglutide injection - once-weekly self-administered injection, starting at $69/month (on a 12 month program) or $79 if they go with a monthly program (no price increases to this, ever)
  • Compounded Tirzepatide injection - once-weekly GLP-1/GIP dual agonist, starting at $119/month (on a 12 month program) or $129 if they go with a monthly program (no price increases to this, ever)

Do I Need a Prescription?

Yes. A licensed U.S. provider reviews your health intake and prescribes if appropriate.

Delivery:

Medication ships free in 1–2 days in discreet packaging. Unlimited 24/7 provider and support access included.

Costs:

Compounded Semaglutide starts at $69/month on a 12-month program with no membership fees or hidden charges. HSA/FSA approved; no insurance required.

Commitment:

No long-term contract. Month-to-month plans can be cancelled anytime.10

Go to Embody
arrow imageLeaving WebMD

About Direct Meds

Direct Meds is a fully integrated telehealth platform that supports over 200 prescribed therapies, including life-changing medications like GLP-1s for weight loss, longevity peptides, and hormone therapy. They operate through a network of licensed U.S. physicians in all 50 states, with medication compounded by US-based pharmacies, delivered directly to your door in under 48 hours.

Weight Loss Treatments Offered:

  • Compounded Semaglutide injections
  • Compounded Tirzepatide injections

Do I Need a Prescription?

Yes. A licensed physician reviews your online intake, within 24 hours (often less than 5 hours), and prescribes if appropriate.

Delivery:

Medication ships within 48 hours via FedEx or UPS in temperature-controlled packaging; orders placed before 2pm CT ship the same day.

Costs:

Compounded semaglutide injections start at $69/month with Direct Meds' promotional pricing. This pricing is locked in for life. Compounded tirzepatide starts at $119 for the first month under Direct Meds' promotional pricing, including $100 off. Your price is guaranteed. No membership or access fees; HSA and FSA accepted.

Commitment:

No long-term contract on month-to-month pricing; subscribe-and-save plans available for an additional discount. Cancel anytime by email or phone; full refund if your prescription isn't approved.11

Go to Direct Meds
arrow imageLeaving WebMD

About MEDVi:

MEDVi offers powerful GLP-1 weight loss medications, including injections and tablets, with no insurance or membership fees required. Start with a personalized plan and get doctor-led support 24/7.

Weight Loss Treatments Offered:

Personalized GLP-1 medications including Semaglutide and Ozempic®, designed to help you lose up to 40 lbs and maintain long-term results.

Do I Need a Prescription?

Yes. MEDVi's medical team will prescribe treatment based on your health profile after your online consultation.

Delivery:

Medications are shipped directly to your door for maximum privacy and convenience.

Costs:

Transparent monthly pricing with no hidden fees or memberships. Plans start at just $149/month, with a money-back guarantee if results aren't achieved.

Commitment:

No long-term contract is needed. MEDVi operates month-to-month, and you can cancel anytime.12

Go to MEDVi
arrow imageLeaving WebMD

About SnagRx:

SnagRx is a telehealth platform that provides eligible patients access to compounded semaglutide and tirzepatide for weight loss, prescribed by licensed US doctors. No hidden fees, and the medication is shipped directly to your home in 1-2 days.

Weight Loss Treatments Offered:

  • Compounded semaglutide once-weekly self-administered injection
  • Compounded tirzepatide once-weekly GLP-1/GIP dual agonist injection
  • Flat pricing at every dose, no hidden fees or monthly membership

Do I Need a Prescription?

Yes. A licensed provider reviews your online intake, typically within 24 hours, and prescribes if appropriate.

Delivery:

Medication ships free via 1-2 day delivery from US-licensed 503A pharmacies; orders placed before 2pm CT often ship the same day.

Costs:

Compounded semaglutide currently starts at $69/month and compounded tirzepatide starts at $119/month. Prescription & telemed visits included. No membership fees or hidden fees.

Commitment:

No long-term contract on month-to-month pricing. Cancel anytime; full refund if your prescription isn't approved.13

Go to SnagRx
arrow imageLeaving WebMD

About Sprout Health:

Sprout offers a fast, affordable way to access GLP-1 medications like Semaglutide. Take a quick quiz, get prescribed online, and receive fast shipping—no hidden fees or insurance required.

Weight Loss Treatments Offered:

Compounded semaglutide and compounded tirzepatide, prescribed by a US-licensed clinician after an online evaluation for eligible patients. Wegovy® (semaglutide) and Zepbound® (tirzepatide) are also available through the platform for qualified individuals.

Do I Need a Prescription?

Yes. Sprout doctors will prescribe if medically qualified, after your 2-minute online quiz and evaluation.

Delivery:

Discreet, refrigerated delivery nationwide, typically within 3–7 business days of prescription.

Costs:

Compounded semaglutide starts at $149/month; compounded tirzepatide starts at $199/month. Flat-rate pricing across all dosages — no membership fees, no hidden charges.

Commitment:

No contracts. Monthly subscription model with the freedom to cancel anytime.14

Go to Sprout Health
arrow imageLeaving WebMD

About Bodybuilding Health+:

Bodybuilding Health+ offers science-backed treatments designed to support sustainable weight loss and metabolic health under the guidance of licensed providers. They offer compounded Semaglutide — available as an injectable or oral microdose — with flexible bundle pricing and no monthly membership fees.

Weight Loss Treatments Offered:

  • Compounded injectable Semaglutide — once-weekly injection, if prescribed
  • Oral Semaglutide microdose — lower-dose daily option, if clinically appropriate
  • Compounded injectable Tirzepatide, if prescribed
  • Oral Tirzepatide microdose, if clinically appropriate

Do I Need a Prescription?

Yes. After completing an online health assessment, a licensed provider reviews your goals and medical history and prescribes the most suitable program, if eligible.

Delivery:

The entire process is handled online — no in-person visits, no waiting rooms. Medication ships directly to your door from FDA registered pharmacies.

Costs:

Compounded injectable Semaglutide starts at $179/month (single) or as low as $141.50/month on a 12-month bundle, saving up to $450/year. Oral microdose Semaglutide from $179/month (single) or $159/month on a 3-month plan. No monthly membership fees, no hidden costs.

Commitment:

No long-term contract required. Plans are flexible and can be adjusted or cancelled anytime. Available as single-month, 3-month, 6-month, and 12-month bundles.15

Conclusion

Ro and welludr. stand out as top choices for anyone looking to tackle weight loss with affordable GLP-1 meds. Embody also makes things easy with quick online consultations, sending meds right to your door.

All the options on this list offer personal care based on your own weight loss journey from home. So, if losing weight is your goal in 2026, get started by checking out one of the top-ranked providers above.

Editorial note: All information is based on data available at the time of publication and may not reflect current offerings. Please visit each platform's website for the most accurate and up-to-date details.

Ratings reflect an independent review conducted by the team at Apex Point Partners, maintained independently of each company's licensing, clinician oversight, pricing, medication access, and patient experience, and are updated regularly.

Medical Disclaimer: The content on this page is provided for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Nothing here is intended to promote any specific medication or guarantee any particular outcome. Prescription medications, including GLP-1 receptor agonists, are available only through a licensed healthcare provider and may not be appropriate for everyone. Individual results vary. Always consult a qualified healthcare provider before starting, stopping, or changing any medication or treatment plan.

The above partners may provide compounded medications that are not FDA-approved or evaluated for safety, efficacy, or quality. Please talk to your provider to determine if a compounded GLP-1 medication is right for you.

Sources

  1. https://www.ncbi.nlm.nih.gov/books/NBK551568/
  2. https://pmc.ncbi.nlm.nih.gov/articles/PMC8717485/
  3. https://www.fda.gov/news-events/press-announcements/fda-approves-fourth-product-under-national-priority-voucher-program-higher-dose-semaglutide
  4. https://www.fda.gov/news-events/press-announcements/fda-approves-new-medication-chronic-weight-management
  5. https://www.ncbi.nlm.nih.gov/books/NBK603723/
  6. https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/215256s033lbl.pdf
  7. https://pmc.ncbi.nlm.nih.gov/articles/PMC12264624/
  8. https://ro.co/weight-loss/#weight-loss-faqs
  9. https://www.wellmedr.com/pages/faq
  10. https://joinem.co/#faq
  11. https://directmeds.com/how-it-works
  12. https://glp1.medvi.org/#faq
  13. https://snagrx.com/#faqs
  14. https://joinsprouthealth.com/how-it-works/
  15. https://bbhealthplus.com/